![]() Compared to controls, subcutaneous and intra-abdominal fat reduced significantly with both diet (- 12.5% and - 12.0%) and exercise plus diet (- 16.0% and - 14.6%). ![]() The diet and exercise plus diet group lost 6.1 and 6.9% body weight, respectively. Outcomes after 16 weeks are amount and distribution of abdominal fat, measured by magnetic resonance imaging (MRI) with the use of the three-point IDEAL Dixon method. Both intervention groups aimed for equivalent weight loss (6-7%) following a calorie-restricted diet (diet group) or a partly supervised intensive exercise programme (4 h per week) combined with a small caloric restriction (exercise plus diet group). Postmenopausal overweight women were randomized to a diet (n = 97), exercise plus diet (n = 98) or control group (n = 48). The SHAPE-2 study is a three-armed randomised controlled trial conducted in 2012-2013 in the Netherlands. assessed the effect of equivalent weight loss with or without exercise on (intra-) abdominal fat in postmenopausal women in the SHAPE-2 study. 7 Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, STR 6.131, Universiteitsweg 100, 3584 CG, Utrecht, the Netherlands. ![]() 6 Department of Health Sciences, EMGO Institute for Health and Care Research, VU University, Amsterdam, the Netherlands.5 Division of Public Health and Health Care, National Institute for Public Health and the Environment, Bilthoven, the Netherlands. ![]()
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